Wei Li, Ph.D.
Professor and Director
Department of Dermatology and the Norris Comprehensive Cancer Center, University of Southern California Keck Medical Center,
Los Angeles, California, USA
The title of the lecture:
Extracellular Heat Shock Protein-90 (Hsp90) in Tumor Survival, Invasion and Metastasis
After receiving his college education in China, Wei Li came to the US in 1984. He received MS degree in 1988 and PhD degree in 1991 under supervision of Dr. E Richard Stanley from the Albert Einstein College of Medicine, Bronx, New York. Following a 18-month post-doctoral/instructor fellowship with Dr. Joseph Schlessinger (Professor and Chairman, the Department of Pharmacology at New York University Medical Center), he joined the faculty of the Ben May Institute for Cancer Research at the University of Chicago in the fall of 1993 as an Assistant Professor on tenure track. He was recruited to University of Southern California (USC) Keck School of Medicine in 1999. He rose to full professor in 2006. He is currently a Professor and Director of the GMCB Graduate Program at USC Keck School of Medicine.
His research interest focuses wound healing and cancer progression. His lab is the first to identify the important role for the SECRETED form of heat shock protein-90 (Hsp90) in skin wound healing, as well as in tumor cell motility, invasion and metastasis. He holds four patents on secreted Hsp90 as a drug candidate to treat chronic wounds and triple negative breast cancer and all the patents have entered their industrial development phases. His research program is currently supported by two NIH grants (RO1) and one VA research grant (with Dr. David Woodley, MD). He is the principle or co- author of more than 74 peer-reviews publications in biomedical journals, including Cell, Nature, Science, PNAS, Nature Medicine, Journal of Clinical Investigation (JCI), EMBO J, Molecular Cell Biology (MCB), Molecular Biology of Cell (MBC), Journal of Cell Biology (JCB), JCS and JBC. He is a frequent speaker at national and international levels. His four recent representative publications are: Li et al, EMBO J. (2007) 26:1121-1133; Cheng et al, (2011) J Clinic. Invest. 121:4348-4361; Sahu et al. (2012) Mol. Biol. Cell. 23:602-613 and Tsen et al. (2013) Mol Cell Biol., 33:4947-4953.